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Older adults may be more sensitive to the side effects of this drug, especially mental/mood changes (such as confusion, agitation) and kidney problems (such as a change in the amount of urine).
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Aunque Glaxo tenía un acuerdo con ICOS para compartir los beneficios 50/50 de fármacos derivados de la asociación, dejó que venciera el acuerdo en 1996 alegando que los medicamentos desarrollados no estaban en los principales mercados de la compañía.
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